On September 2, 2005, Yamada, Rintaro; Seto, Minoru published a patent.Related Products of 58142-46-4 The title of the patent was Preparation of isoquinoline derivatives as inhibitors of myosins light chain phosphorylation. And the patent contained the following:
The title compounds I [wherein R1 = H, halo, OH, NH2, or alkoxy; R2 = H, halo, alkyl, etc.; R3 = (un)substituted OH, NH2, or SO2NH2] or salts thereof are prepared as inhibitors of myosins light chain phosphorylation for the treatment of glaucoma, chronic obstructive pulmonary disease, asthma, etc. For example, the compound II•xHCl was prepared II•xHCl inhibited human myosins light chain phosphorylation with IC50 of 0.8 μM. The experimental process involved the reaction of 4-Bromo-5-nitroisoquinoline(cas: 58142-46-4).Related Products of 58142-46-4
The Article related to isoquinoline preparation inhibitor myosin regulatory light chain phosphorylation obstruction, human treatment glaucoma chronic obstructive pulmonary disease asthma, Heterocyclic Compounds (One Hetero Atom): Quinolines and Isoquinolines and other aspects.Related Products of 58142-46-4
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem