Alfinito, Eleonora published the artcileSmell Nanobiosensors: Hybrid systems based on the electrical response to odorant capture.Theory And Experiment, Application In Synthesis of 1205-17-0, the main research area is olfactory receptor 17 GPCR rhodopsin nanobiosensor odorant elec impedance.
Mammalian olfactory system is the bio-archetype of smell sensor devices. It is based on a very articulated mechanism which translate the odorant capture information performed by the olfactory receptors (ORs) into a code. Finally, the code is sent to the brain for aroma recognition. Our aim is to partially mimic this system to produce a biosensor on nanometric scale. The active part of the device is constituted of nanosomes containing specific ORs. Each nanosome is interfaced with nanoelectrodes and the odorant capture is converted into an elec. signal. Specifically, the elec. response is correlated with the conformational change that a single OR undergoes when it captures a specific odorant mol. An array of nanodevices should be able to produce specific response profiles. In this paper we present a possible theor. framework in which the exptl. results should be embedded. It consists of the description of the protein in terms of an impedance network able to simulate the elec. characteristics associated with the protein topol. (c) 2009 American Institute of Physics.
AIP Conference Proceedings published new progress about Biosensors. 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Application In Synthesis of 1205-17-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem