Li, Qian published the artcileA G-quadruplex based fluorescent oligonucleotide turn-on probe towards iodides detection in real samples, Application In Synthesis of 117-96-4, the main research area is iodide G quadruplex fluorescent oligonucleotide probe food; Biological samples; Drugs; Fluorescence oligonucleotide probe; Food; Iodide; Water.
A basket-type G-quadruplex (GQ) fluorescent oligonucleotide (OND) probe is designed to detect iodides dependent on thymine-Hg(II)-thymine (T-Hg(II)-T) base pairs and the intrinsic fluorescence quenching capacity of GQ. In the presence of Hg(II) ions (Hg2+), the two hexachloro-fluorescein-labeled ONDs form a hairpin structure and the fluorophores are dragged close to the GQ, leading to fluorescence quenching of the probe due to photoinduced electron transfer. Upon addition of iodide anions, Hg2+ are extracted from T-Hg(II)-T complexes which attributes to the stronger binding with iodide anions, resulting in the fluorescence recovery. Through performing the fluorescence quenching and recovery processes, this probe developed a fluorescence turn-on sensor for iodide anions determination over a linear range of 20-200 nmol/L with a limit of detection of 5 nmol/L. The practical use of the turn-on technol. was demonstrated by its application in determination of iodides in water, food, pharmaceutical products and biol. samples.
Food Chemistry published new progress about Blood serum. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Application In Synthesis of 117-96-4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem