Kim, Bohyun’s team published research in European radiology in 2015-01-11 | CAS: 117-96-4

European radiology published new progress in MEDLINE about 117-96-4, 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Computed Properties of 117-96-4.

Kim, Bohyun published the artcileIohexol versus diatrizoate for fecal/fluid tagging during CT colonography performed with cathartic preparation: comparison of examination quality., Computed Properties of 117-96-4, the main research area is .

OBJECTIVE: We aimed to compare iohexol vs. diatrizoate as fecal/fluid tagging agents for computed tomography colonography (CTC) regarding examination quality. METHODS: Forty prospective patients (M:Fâ€?â€?3:17; 63 ±â€?1.6 years) received CTC using 50 mL (350 mgI/mL) oral iohexol for tagging. Forty other indication-matched, age-matched, and sex-matched patients who underwent CTC using 100 mL diatrizoate for tagging and otherwise the same technique, were retrospectively identified. Two groups were compared regarding overall examination quality, per-patient and per-segment scores of colonic bubbles (0 [no bubbles] to 5 [the largest amount]), and the volume, attenuation, and homogeneity (untagged, layered, and homogeneous) of the residual colonic fluid. RESULTS: The iohexol group demonstrated a greater amount of colonic bubbles than the diatrizoate group: mean per-patient scores ± SD of 1.2 ±â€?.8 vs. 0.7 ±â€?.6, respectively (pâ€?â€?.003); and rates of segments showing ≥ grade 3 bubbles of 12.9 % (85/659) vs. 1.6 % (11/695), respectively (pâ€?â€?.001). Residual colonic fluid amount standardized to the colonic volume did not significantly differ: 7.2 % ±â€?.2 vs. 7.8 % ±â€?.7, respectively (pâ€?â€?.544). Tagged fluid attenuation was mostly comparable between groups and the fluid was homogeneously tagged in 98.7 % (224/227) vs. 99.5 % (218/219) segments, respectively (pâ€?â€?.344). Iohexol caused more colonic bubbles when used during cathartic CTC. Otherwise, examination quality was similarly adequate with both iohexol and diatrizoate. KEY POINTS: â€?When used for tagging, iohexol caused significantly more colonic bubbles than diatrizoate. â€?The residual colonic fluid amount did not significantly differ between iohexol and diatrizoate. â€?The quality of fluid tagging was similarly adequate in both iohexol and diatrizoate.

European radiology published new progress in MEDLINE about 117-96-4, 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Computed Properties of 117-96-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem