Tak, Jun-Hyung published the artcileScreening for enhancement of permethrin toxicity by plant essential oils against adult females of the yellow fever mosquito (Diptera: Culicidae), Synthetic Route of 1205-17-0, the main research area is Diptera Culicidae fever permethrin toxicity essential oil screening; chlorpyrifos-methyl; cucumber seed oil; insecticide synergism; plant essential oils.
Aedes aegypti L. (Diptera: Culicidae) is one of the most medically important mosquito species, due to its ability to spread viruses of yellow fever, dengue fever, and Zika in humans. In this study, the insecticidal activity of 17 plant essential oils was evaluated via topical application against two strains of Ae. aegypti mosquito, Orlando (insecticide-susceptible) and Puerto Rico (pyrethroid-resistant). Initial screens with the Orlando strain showed that cucumber seed oil (2017 sample) was the most toxic, followed by sandalwood and thyme oil. When the essential oils were mixed with permethrin, they failed to show any significant synergism of insecticidal activity. Sandalwood and thyme oils displayed consistently high mortality against the resistant Puerto Rico strain, with low resistance ratios of 2.1 and 1.4, resp. In contrast, cucumber seed oil showed significantly less activity against Puerto Rico mosquitoes, with a resistance ratio of 45. Bioactivity-guided fractionation of the 2017 sample of cucumber seed oil sample via flash column chromatog. produced 11 fractions, and gas-chromatog./mass spectrometry anal. revealed that the three active fractions were contaminated with 0.33, 0.36, and 0.33% of chlorpyrifos-Me, an organophosphorus insecticide, whereas inactive fractions did not show any trace of it. These results suggested that the insecticidal activity of cucumber seed oil was probably due to the presence of the insecticide, later confirmed with a clean batch of cucumber seed oil obtained in 2018, which showed negligible insecticidal activity. These findings demonstrate clearly the need for essential oil anal. to confirm purity before any claims are made about pesticidal potency.
Journal of Medical Entomology published new progress about Adult, mammalian. 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Synthetic Route of 1205-17-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem