Zhong, Dayou published the artcileIron-Catalyzed Intramolecular C-H Amidation of N-Benzoyloxyureas, SDS of cas: 104-01-8, the main research area is arylimidazolidinone preparation; dihydro benzoimidazolon preparation; nitrogen benzoyloxyurea intramol carbon hydroen amidation catalyst iron.
A redox-neutral Fe-catalyzed intramol. C-H amidation of N-benzoyloxyureas was described. This methodol. employed a simple iron complex in situ generated from Fe(OTf)2 and bipyridine as the catalyst and N-benzoyloxyureas as the nitrene precursors without using exogenous oxidants. An array of cyclic ureas I [R1 = Me, n-hexane, Bn, etc.; R2 = Me, Ph, 2-naphthyl, etc.; R3 = H, Me] were synthesized via aliphatic C(sp3)-H amidation in excellent yields. In addition, this catalytic system was also amenable to aryl C(sp2)-H nitrene insertion to provide benzimidazolones II [R1 = Me; R4 = H, MeO, t-Bu, C(O)OMe] in moderate yields.
Chinese Journal of Chemistry published new progress about Amidation (C-H). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, SDS of cas: 104-01-8.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem