Photochemistry of methoxy-substituted quinoline and isoquinoline N-oxides was written by Albini, Angelo;Fasani, Elisa;Dacrema, Lucia Maggi. And the article was included in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) in 1980.Reference of 36034-54-5 This article mentions the following:
Irradiation of methoxyquinoline and -isoquinoline N-oxides gave a variety of photoisomers as well as deoxygenation and secondary reaction products, the nature of the products being dependent on the solvent and the position of the -OMe group. E.g., the irradiation of I (R = H, R1 = OMe) (medium-pressure Hg vapor lamp, 15°) gave 83% II in H2O whereas in C6H6 50% III (R = H, R1 = OMe) was obtained; however I (R = OMe, R1 = H) gave, under the same conditions, o-HOC6H4CH:CHNHCO2Me and IV (22 and 22%, resp.) in water, and III (R = OMe, R1 = H) (40%) in C6H12. In the experiment, the researchers used many compounds, for example, 4-Methoxyisoquinoline (cas: 36034-54-5Reference of 36034-54-5).
4-Methoxyisoquinoline (cas: 36034-54-5) belongs to isoquinoline derivatives. Quinoline and isoquinoline skeletons are among the most attractive frameworks with a wide range of biological and pharmacological activities. The discovery of chloroquine, the most well-known drug containing this stent, has helped bring about decades of malaria control and treatment.Reference of 36034-54-5
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem