Electronic properties of N-heteroaromatics. XXXIV. Fluorescence of isoquinoline derivatives, with special reference to solvent and external heavy atom effects was written by Okano, Teisuke;Matsumoto, Hitoshi. And the article was included in Yakugaku Zasshi in 1969.Computed Properties of C9H7ClN2 This article mentions the following:
Fluorescence spectra of isoquinoline derivatives were measured in various solvents in view of the solvent effect and the external heavy atom effect. The fluorescence of isoquinoline and its 1-cyano, 1-chloro, and 1-diacetylamino (m. 93-4°) derivatives was intensified in hydroxylic solvents, whereas the intensities of 1-amino-, 1-dimethylamino-(b5 124-6°), 1-methoxy-, and 3-aminoisoquinoline and of iso-carbostyril were independent of the solvent. The fluorescence intensification in hydroxylic solvents was attributed to the reversal of 1(π-π*) and 3(n-π*) levels caused by H bonding between the solute and the solvent, considering the intersystem crossing theory of El-Sayed (1963). The fluorescence of 1-aminoisoquinoline, its 3-chloro derivative, 1-chloro- and 2-methyl-3-aminoisoquinoline, and 3-aminoisocarbostyril in EtOH was quenched by addition of CCl4 or CBr4. Presumably, the external heavy atoms caused the spin-orbit coupling between the excited singlet and triplet states. In the experiment, the researchers used many compounds, for example, 3-Chloroisoquinolin-1-amine (cas: 7574-67-6Computed Properties of C9H7ClN2).
3-Chloroisoquinolin-1-amine (cas: 7574-67-6) belongs to isoquinoline derivatives. Quinoline and isoquinoline skeletons are among the most attractive frameworks with a wide range of biological and pharmacological activities. The Pomeranz–Fritsch reaction provides a method for the preparation of isoquinoline. This reaction uses a benzaldehyde and aminoacetoaldehyde diethyl acetal, which in an acid medium react to form isoquinoline.Computed Properties of C9H7ClN2
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem