Ultrafast labeling and high-fidelity imaging of mitochondria in cancer cells using an aggregation-enhanced emission fluorescent probe was written by Liu, Li;Zou, Qian;Leung, Jong-Kai;Wang, Jia-Li;Kam, Chuen;Chen, Sijie;Feng, Shun;Wu, Ming-Yu. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Electric Literature of C15H13N This article mentions the following:
An aggregation-enhanced emission mitochondrial probe, LIQ-3 (I), was developed for ultrafast labeling within one minute and for distinguishing cancer cells from normal cells. Furthermore, the probe revealed high-fidelity tracking of mitochondria in a three-dimensional localization with advantages that include a specific targeting capacity and a high signal-to-noise ratio. In the experiment, the researchers used many compounds, for example, 1-Phenyl-3,4-dihydroisoquinoline (cas: 52250-50-7Electric Literature of C15H13N).
1-Phenyl-3,4-dihydroisoquinoline (cas: 52250-50-7) belongs to isoquinoline derivatives. Quinoline and isoquinoline skeletons are among the most attractive frameworks with a wide range of biological and pharmacological activities. The discovery of chloroquine, the most well-known drug containing this stent, has helped bring about decades of malaria control and treatment.Electric Literature of C15H13N
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem