Pd-Catalyzed arylation/oxidation of benzylic C-H bond was written by Xie, Yongju;Yang, Yuzhu;Huang, Lehao;Zhang, Xunbin;Zhang, Yuhong. And the article was included in Organic Letters in 2012.COA of Formula: C10H7NO2 This article mentions the following:
A palladium-catalyzed benzylic C-H arylation/oxidation reaction leading to diaryl ketones, e.g., I, has been accomplished. The indispensable role of the bidentate system is disclosed for this sequential process. This chem. offers a direct new access to a range of diaryl ketones. In the experiment, the researchers used many compounds, for example, Isoquinoline-1-carboxylic acid (cas: 486-73-7COA of Formula: C10H7NO2).
Isoquinoline-1-carboxylic acid (cas: 486-73-7) belongs to isoquinoline derivatives. Isoquinoline is a structural isomer of quinoline, which have antiseptic, antipyretic and anti-cyclic properties, and can be used as antimalarial drugs and for the preparation of other antimalarial medicine. It protonates to form salts upon treatment with strong acids, such as HCl. It forms adducts with Lewis acids, such as BF3.COA of Formula: C10H7NO2
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem