Bacteriostasis test on chuanhuning-berberine injection in vitro was written by Zeng, Yan;He, Yue-lin;Zhou, Ying-hua;Zeng, De-yong;Chen, Xian;Li, Qiu-yun. And the article was included in Zhongshouyi Yiyao Zazhi in 2008.Reference of 316-41-6 This article mentions the following:
The chuanhuning is the monopotassium salt of 14-deoxy-11,12- didehydroandrographolide-3,19-disuccinate formed by the andrographolide and succinic anhydride’s dehydration and esterification, salification. The berberine sulfate is the typical delegate of the isoquinoline anti bacteria drugs. In this paper, the in vitro bacteriostasis test of the complex chuanhuning-berberine injection is specially carried on to observe the synergistic reaction between chuanhuning and berberine. In the experiment, the researchers used many compounds, for example, 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium sulfate(2:1) (cas: 316-41-6Reference of 316-41-6).
9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium sulfate(2:1) (cas: 316-41-6) belongs to isoquinoline derivatives. Quinoline and its derivatives are widely used as fungicides, biological agents, antibiotics, alkaloids, dyes, rubber chemicals and flavoring agents. Other industrial applications include their use as corrosion inhibitors, preservatives, and as solvents for resins and terpenes.Reference of 316-41-6
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem