Chuang, Ta-Hsien et al. published their research in Journal of Organic Chemistry in 2013 | CAS: 491-30-5

1-Hydroxyisoquinoline (cas: 491-30-5) belongs to isoquinoline derivatives. Quinoline and isoquinoline skeletons are among the most attractive frameworks with a wide range of biological and pharmacological activities. The discovery of chloroquine, the most well-known drug containing this stent, has helped bring about decades of malaria control and treatment.Formula: C9H7NO

Direct Conversion of 1-(2-Bromobenzoyl)isoquinolines to Dibenzo[de,g]quinolin-7-ones via Reductive Photocyclization was written by Chuang, Ta-Hsien;Li, Chien-Fu;Lee, Hong-Zin;Wen, Yu-Chia. And the article was included in Journal of Organic Chemistry in 2013.Formula: C9H7NO This article mentions the following:

A series of A/D-ring substituted dibenzo[de,g]quinolin-7-ones I (R1 – R4 = H, MeO; R2R3 = OCH2O; R5 = H, MeO, CF3; R4R5 = OCH2O) was produced from the corresponding isoquinolinones II and (2-bromophenyl)acetonitriles III in four steps. This represents a convenient approach toward the synthesis of tetracyclic alkaloids. A direct conversion of 1-(2-bromobenzoyl)isoquinolines IV to dibenzo[de,g]quinolin-7-ones I is the key step in the total synthesis. The yield of the reductive photocyclization depends on the position of the substituents at the isoquinolyl ring and the Ph group. The mechanism of the reductive photocyclization is also discussed. In the experiment, the researchers used many compounds, for example, 1-Hydroxyisoquinoline (cas: 491-30-5Formula: C9H7NO).

1-Hydroxyisoquinoline (cas: 491-30-5) belongs to isoquinoline derivatives. Quinoline and isoquinoline skeletons are among the most attractive frameworks with a wide range of biological and pharmacological activities. The discovery of chloroquine, the most well-known drug containing this stent, has helped bring about decades of malaria control and treatment.Formula: C9H7NO

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem