Three-component coupling of isoquinoline, activated alkyne and nitromethane: a facile synthesis of nitromethyl derivatives of 1,2-dihydroisoquinolines was written by Yadav, Jhillu S.;Reddy, Basi V. Subba;Yadav, Nagendra Nath;Gupta, Manoj K.. And the article was included in Synthesis in 2009.Category: isoquinoline This article mentions the following:
A 3-component coupling (3CC) of isoquinoline, activated alkynes, and MeNO2 was achieved to produce (nitromethyl)dihydroisoquinolines in excellent yields with high selectivity. The reaction proceeds smoothly at 25掳C without catalyst. In the experiment, the researchers used many compounds, for example, 5-Nitroisoquinoline (cas: 607-32-9Category: isoquinoline).
5-Nitroisoquinoline (cas: 607-32-9) belongs to isoquinoline derivatives. Quinoline is a mancude organic heterobicyclic parent, an azaarene, an ortho-fused heteroarene and a member of isoquinolines. Most traditional methods of generating isoquinoline do so via oxidative aromatization of dihydro- or tetrahydro-isoquinolines, usually offering some environmental or economic advantage.Category: isoquinoline
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem