Brief introduction of 19493-45-9

As the paragraph descriping shows that 19493-45-9 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.19493-45-9,3-Chloroisoquinoline,as a common compound, the synthetic route is as follows.

EXAMPLE 2 3-(Piperazin-1-yl)-isoquinoline 2.0 g of 3-chloroisoquinoline are boiled under reflux for 120 hours with 20 g of piperazine in 100 ml of diethylene glycol dimethyl ether. Working up as in Example 1 gives 2.4 g of 3-(piperazin-1-yl)-isoquinoline, melting point 95-96; its hydrochloride decomposes at 266-268 C.

As the paragraph descriping shows that 19493-45-9 is playing an increasingly important role.

Reference£º
Patent; Hoechst Aktiengesellschaft; US4590273; (1986); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem