Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Product Details of 1532-97-4. Introducing a new discovery about 1532-97-4, Name is 4-Bromoisoquinoline
Regioselective Chlorination of Quinoline N-Oxides and Isoquinoline N-Oxides Using PPh3/Cl3CCN
A novel method for the regioselective C2-chlorination of heterocyclic N-oxides has been developed. PPh3/Cl3CCN were used as chlorinating reagents and the desired N-heterocyclic chlorides were obtained smoothly in satisfactory yields. The reactions proceeded in a highly efficient and selective manner across a broad range of substrates demonstrating excellent functional group tolerance. In addition, this chlorination reaction can be used for the modification of N-heterocyclic scaffolds of appealing ligands and pharmaceuticals.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 1532-97-4, you can also check out more blogs about1532-97-4
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem