With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.23687-25-4,Isoquinolin-4-amine,as a common compound, the synthetic route is as follows.
4-Aminoisoquinoline (27 mg, 0.19 mmol), final product 03 (20 mg, 0.062 mmol) and Et3N (25 mg, 0.25 mmol) were weighed into a bottle, and DMF was added to dissolve the reaction reagent.The reaction was heated at 50 C overnight.The crude reaction product was directly purified by reverse phase HPLC to obtain the target compound YD028 (24.4 mg)., 23687-25-4
The synthetic route of 23687-25-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Zhao Yujun; Li Jia; Wang Zengtao; Zhang Shiyan; Zang Yi; Wang Peipei; Sun Dandan; Zhang Hanyan; (155 pag.)CN110818683; (2020); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem