Extracurricular laboratory:new discovery of 1532-97-4

If you are interested in 1532-97-4, you can contact me at any time and look forward to more communication. Formula: C9H6BrN

Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C9H6BrN, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 1532-97-4

6,6-Fused heterocyclic ureas as highly potent TRPV1 antagonists

A series of N-[{2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)-pyridin-3-yl}methyl] N?-(6,6-fused heterocyclic) ureas have been investigated as hTRPV1 antagonists. Among them, compound 15 showed highly potent TRPV1 antagonism to capsaicin, with Ki(ant) = 0.2 nM, as well as antagonism to other activators, and it was efficacious in a pain model. A docking study of 15 with our hTRPV1 homology model indicates that there is crucial hydrogen bonding between the ring nitrogen and the receptor, contributing to its potency.

If you are interested in 1532-97-4, you can contact me at any time and look forward to more communication. Formula: C9H6BrN

Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H3368N – PubChem