With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34784-02-6,3-Bromoisoquinoline,as a common compound, the synthetic route is as follows.
20mmol S15-1, 30.0mmol S15-2, 0.20mmol palladium(II)acetate catalyst and 36mmol trihydrate Potassium phosphate, dissolved in 30mL toluene: ethanol: water in a mixed solvent of water (2:1:2), it was heated at 70 C for 12 h. It was cooled and extracted with dichloromethane (50 mL¡Á3) three times. The organic phase was collected and purified by silica gel column chromatography eluting with petroleum ether:dichloromethane (10:1) to give solid S15-3 8.9 mmol (yield: 44.7%), 34784-02-6
As the paragraph descriping shows that 34784-02-6 is playing an increasingly important role.
Reference£º
Patent; Ruisheng Science And Technology (Singapore) Co., Ltd.; Cao Chenhui; Huang Da; (54 pag.)CN108191916; (2018); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem