Chemistry is traditionally divided into organic and inorganic chemistry. Quality Control of 4-Iodoisoquinoline, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 55270-33-2
An oxidative multi-functionalization of azaarenes with benzylic C[sbnd]H bonds of methylarenes via iodination/N-benzylation/amidation cascade, to produce N-benzyl-4-iodoisoquinolin-1(2H)-ones and N-benzyl-3-iodoquinolin-2(1H)-ones is developed. The molecular iodine plays a triple role in activating benzylic sp3 C[sbnd]H bond of methylbenzenes, accelerating the oxidation process and serving as iodination reagent. This reaction utilizes cheap and readily available azaarenes and methylarenes as starting materials and proceeds under metal-free conditions to construct C-I, C[sbnd]N and C[dbnd]O bonds consecutively and afford iodo(iso)quinolinones efficiently.
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Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem