486-73-7, Name is Isoquinoline-1-carboxylic acid, belongs to isoquinoline compound, is a common compound. COA of Formula: C10H7NO2In an article, once mentioned the new application about 486-73-7.
A convenient and efficient method for the synthesis of 2-halogen-substituted pyridines is described. The decarboxylative halogenation of 2-picolinic acids with dihalomethane proceeded smoothly via N-chlorocarbene intermediates to afford 2-halogen-substituted pyridines in satisfactory to excellent yields under transition-metal-free conditions. This new type of decarboxylative halogenation is operationally simple and exhibits high functional-group tolerance.
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Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H1980N – PubChem