With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.216099-46-6,6-Aminoisoquinolin-1-ol,as a common compound, the synthetic route is as follows.
Example 13Synthesis of 1-benzyl-3-(1-oxo-1,2-dihydro-isoquinolin-6-yl)-urea. Method 4 6-Amino-2H-isoquinolin-1-one (0.2 mmol, 39 mg) and benzyl isocyanate (0.2 mmol, 27 mg) were dissolved in 1 mL DMA. The mixture was allowed to stir at 60 C. overnight. The product was obtained by HPLC purification. MS (M+1) 294., 216099-46-6
The synthetic route of 216099-46-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Young, Erick Richard; Liu, Weimin; Prokopowicz, Anthony S.; Schlyer, Sabine K.; Shih, Cheng-Kon; Snow, Roger John; Bosanac, Todd; Ginn, John David; Hickey, Eugene Richard; Kirrane, Thomas Martin; Turner, Michael Robert; Wu, Frank; US2008/161297; (2008); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem