630421-73-7, 1,6-Dichloroisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution/suspension of 4,4,5,5-tetramethyl-2-(10-methylfluoranthen-8-yl)-1,3,2-dioxaborolane (26.6 g, 78 mmol), 1,6-dichloroisoquinoline (14 g, 70.7 mmol) and sodium carbonate (18.73 g, 177 mmol) in DME (471 ml) and water (118 ml) was degassed with bubbling nitrogen for 20 min. Tetrakis(triphenylphosphine)palladium (2.451 g, 2.121 mmol) was added and degassing continued for 5 mins. The reaction mixture was heated at 105 C. (reflux) for 8 h. The mixture was allowed to cool overnight. The reaction mixture was filtered and the remaining solids in the flask were washed out with methanol (200-300 ml). The filter cake was washed with water (200 ml), methanol (200 ml), water (200 ml), and then methanol (200 ml). The solids were dried under air for 30 min then under vacuum over the weekend to yield the title compound as a yellow solid (23.63 g, 88%).
The synthetic route of 630421-73-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Universal Display Corporation; Ji, Zhiqiang; Tsai, Jui-Yi; Dyatkin, Alexey Borisovich; Layek, Suman; Boudreault, Pierre-Luc T.; (175 pag.)US2019/214583; (2019); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem