Sep-14 News Final Thoughts on Chemistry for 1532-97-4

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1532-97-4, Name is 4-Bromoisoquinoline, belongs to isoquinoline compound, is a common compound. Recommanded Product: 4-BromoisoquinolineIn an article, once mentioned the new application about 1532-97-4.

A room-temperature Ni-catalyzed cross-coupling of aryl, heteroaryl, and alkenyl electrophiles with aminoalkylzinc bromides, readily available from the corresponding aminoalkyl chlorides via Grignard reagents, was developed. The reaction allows a convenient one-step preparation of various aminoalkyl products, including piperidine and tropane derivatives. Such functionalized amine moieties are widely present in various biologically active molecules. Aryl, heteroaryl, and alkenyl iodides, bromides, chlorides and triflates are suitable electrophiles. A short total synthesis of two natural products, (±)-galipinine and (±)-cusparine, is also reported.

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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H3275N – PubChem