With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.52986-70-6,6-Methoxyisoquinoline,as a common compound, the synthetic route is as follows.
(c) 6-Methoxyisoquinoline (16 g, 0.1M) and 48% aqueous HBr (600 ml) were refluxed together for 6 hours and the mixture was then evaporated to dryness in vacuo. The residue was dissolved in H2 O and basified with solid Na2 CO3. The resulting precipitated solid was filtered off and recrystallized from isopropanol to give 6-hydroxyisoquinoline (12 g, 82%), m.p. 218-20 C. (lit.* 220 C.).
The synthetic route of 52986-70-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SmithKline & French Laboratories, Ltd.; US4812573; (1989); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem