Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 67929-86-6, is researched, SMILESS is O=C(C(N1)=CC2=C1C=CC(OC)=C2)OC, Molecular C11H11NO3Journal, Article, Research Support, Non-U.S. Gov’t, Chemical Communications (Cambridge, United Kingdom) called Continuous flow thermolysis of azidoacrylates for the synthesis of heterocycles and pharmaceutical intermediates, Author is O’Brien, Alexander G.; Levesque, Francois; Seeberger, Peter H., the main research direction is continuous flow thermolysis azidoacrylate; indole preparation; heterocycle preparation.Quality Control of Methyl 5-methoxyindole-2-carboxylate.
An efficient, safe and scalable procedure for the continuous flow thermolysis of azidoacrylates to yield indoles has been developed and was applied to the synthesis of related heterocycles. The scalability of the process was demonstrated in the continuous flow synthesis of a precursor to the DAAO inhibitor 4H-furo[3,2-b]pyrrole-5-carboxylic acid.
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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem