Isoquinoline is a heterocyclic aromatic organic compound. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. Product Details of C9H6BrN.
Dong, Jianyang;Yue, Fuyang;Song, Hongjian;Liu, Yuxiu;Wang, Qingmin research published 《 Visible-light-mediated photoredox minisci C-H alkylation with alkyl boronic acids using molecular oxygen as an oxidant》, the research content is summarized as follows. A protocol for direct visible-light-mediated Minisci C-H alkylation reactions of heteroarenes, e.g., 4,6-dimethylpyrimidine with alkyl boronic acids RB(OH)2 (R = CH2CH3, C6H5, cyclohexyl, etc.) using mol. oxygen as the sole oxidant has been described. This mild protocol uses an inexpensive, green oxidant, permits efficient functionalization of various N-heteroarenes with a broad range of primary and secondary alkyl boronic acids; and is scalable to the gram level. The practicality and sustainability of the protocol by preparing or functionalizing several pharmaceuticals and natural products have been demonstrated.
Product Details of C9H6BrN, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.
4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem