Isoquinoline’s properties: Isoquinoline is a colorless hygroscopic liquid at temperatures above its melting point with a penetrating, 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. unpleasant odor. Impure samples can appear brownish, as is typical for nitrogen heterocycles. Safety of 4-Bromoisoquinoline.
Stepanova, Victoria A.;Patrushev, Sergey S.;Rybalova, Tatyana V.;Shults, Elvira E. research published 《 Cross-coupling reaction to access a library of eudesmane-type methylene lactones with quinoline or isoquinoline substituent》, the research content is summarized as follows. An efficient and simple protocol for the Heck reaction of accessible natural eudesmane-type methylene lactone isoalantolactone or its derivatives – 4,15-epoxyisoalantolactone, and 3-hydroxyisoalantolactone, with halo-substituted quinolines and isoquinolines using Pd(OAc)2 as the catalyst is presented. The reactions proceed well in DMF and TBAB in the absence of phosphine ligands. The structures of isoalantolactone-quinoline and isoalantolactone-isoquinoline hybrids were analyzed by mass spectrum, elemental anal. and NMR spectral studies. The crystal structure of new compounds was determined from single crystal X-ray diffraction data.
Safety of 4-Bromoisoquinoline, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.
4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem