Zheng, Zhongqi team published research on Tetrahedron in 2022 | 1532-97-4

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., Category: isoquinoline

Isoquinoline can crystallizes in platelets that have a low solubility in water but dissolve well in ethanol, acetone, diethyl ether, carbon disulfide, and other common organic solvents. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is also soluble in dilute acids as the protonated derivative. Category: isoquinoline.

Zheng, Zhongqi;Wu, Yongdi;Lu, Xuelian;Zhang, Fang-Lin;Qi, Mei-Fang;Sun, Enjie;Sun, Bing research published 《 Visible-light-mediated metal-free decarboxylative acylation of electron-deficient quinolines using α-ketoacids under ambient air》, the research content is summarized as follows. A visible-light-promoted metal-free decarboxylative coupling protocol for the acylation of electron-deficient quinolines RH [R = quinolin-1-yl, 6-nitroquinolin-1-yl, 3-methylquinolin-1-yl, etc.] using ambient air as an oxidant has been disclosed. This environmental-friendly protocol takes place under mild conditions and is highlighted by using inexpensive photocatalyst and starting materials, thereby integrating C-H functionalization and recent photoredox scenario based on diaryl ketones RC(O)R1 [R1 = Ph, Me, thiophen-2-yl, etc.]. This work contributes to a more systematic utilization of α-ketoacids R1C(O)OH as an efficient source of acyl radicals in acylation of electron-deficient heteroaromatic compounds

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., Category: isoquinoline

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem