Electric Literature of C9H7ClN2On June 1, 1982, Sawanishi, Hiroyuki; Hirai, Toyoko; Tsuchiya, Takashi published an article in Heterocycles. The article was 《Photolysis of pyridyl, quinolyl, and isoquinolyl azides in hydrohalic acids》. The article mentions the following:
Irradiation of 4-azidopyridine and -quinoline in 6 N HCl or HBr at room temperature gave the corresponding 3-amino-4-halo compound (10-15% yield) and 4-aminopyridine and 4-aminoquinoline (25-35% yield). On the other hand, similar treatment of 4 azidopyridine N-oxide and 4-azidoquinoline N-oxide gave the corresponding 4-amino-3-halo compounds (80-95% yields). Also, similar treatment of 3-azidoquinoline and 4-azidoisoquinoline, both the free bases and the N-oxides, gave results similar to those for 4-azidopyridine N-oxide. Photolysis of 4-azidopyridine and -quinoline occurred through azirine of azacycloheptatetraene intermediates. The photolysis of 4-azidopyridine N-oxide and 4-azidoquinoline N-oxide occurred through nitrenium ion intermediates.3-Chloroisoquinolin-4-amine(cas: 342899-38-1Electric Literature of C9H7ClN2) was used in this study.
3-Chloroisoquinolin-4-amine(cas: 342899-38-1) belongs to isoquinoline.Electric Literature of C9H7ClN2 Isoquinoline is a structural isomer of quinoline, and quinoline derivatives are fused ring compounds of pyridine and benzene rings, which have antiseptic, antipyretic and anti-cyclic properties, and can be used as antimalarial drugs and for the preparation of other antimalarial medicine.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem