On July 1, 2006, Jesudason, Cynthia D.; Beavers, Lisa S.; Cramer, Jeffrey W.; Dill, Joelle; Finley, Don R.; Lindsley, Craig W.; Stevens, F. Craig; Gadski, Robert A.; Oldham, Samuel W.; Pickard, R. Todd; Siedem, Christopher S.; Sindelar, Dana K.; Singh, Ajay; Watson, Brian M.; Hipskind, Philip A. published an article.COA of Formula: C10H11NO2 The title of the article was Synthesis and SAR of novel histamine H3 receptor antagonists. And the article contained the following:
The synthesis and biol. evaluation of novel tetrahydroisoquinoline, tetrahydroquinoline, and tetrahydroazepine antagonists of the human and rat H3 receptors are described. The substitution around these rings as well as the nature of the substituent on nitrogen is explored. Several compounds with high affinity and selectivity for the human and rat H3 receptors are reported. The experimental process involved the reaction of 8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one(cas: 74904-29-3).COA of Formula: C10H11NO2
The Article related to h3 antihistaminic tetrahydroisoquinoline tetrahydroquinoline tetrahydroazepine preparation, Heterocyclic Compounds (One Hetero Atom): Quinolines and Isoquinolines and other aspects.COA of Formula: C10H11NO2
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem