Saadiq, Muhammad published the artcileSynthesis, Bioactivity Assessment, and Molecular Docking of Non-sulfonamide Benzimidazole-Derived N-Acylhydrazone Scaffolds as Carbonic Anhydrase-II Inhibitors, SDS of cas: 86-51-1, the main research area is benzimidazole acylhydrazone preparation mol docking carbonic anhydrase inhibitor.
This research reports the synthesis of new benzimidazole-derived N-acylhydrazones (NAH), their characterization using various spectroscopic methods, and in vitro evaluation as potent carbonic anhydrase-II inhibitors. Among the target compounds, few showed higher inhibition than the standard acetazolamide (IC50: 18.6 ± 0.43μM). Mol. docking was performed on the most active compounds, which revealed their binding interactions with the active site of the enzyme, thus supporting the exptl. findings.
ACS Omega published new progress about Carbonic anhydrase inhibitors. 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, SDS of cas: 86-51-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem