Zanghi, Joseph M. published the artcileEnantio- and Diastereoselective Synthesis of Functionalized Carbocycles by Cu-Catalyzed Borylative Cyclization of Alkynes with Ketones, Safety of 1,3-Dimethoxybenzene, the main research area is diastereoselective copper catalyzed borylative cyclization alkyne ketone alkynylcyclohexanedione; cyclohexandione alkynylation propargyl bromide; diboryl indenone preparation oxidation boryl elimination Martins sulfurane; crystal structure chiral diboryl allyl indenone; mol structure chiral diboryl allyl indenone.
A single-pot Cu-catalyzed enantio- and diastereoselective tandem hydroboration/borylative cyclization of alkynes with ketones for the synthesis of carbocycles is reported. The reaction proceeds via desymmetrization and generates four contiguous stereocenters, including an all-C quaternary center. The method provides rapid access to [6,5]- and [5,5]-bicycles and cyclopentane products. Catalyst-controlled diastereoselectivity by selection of bisphosphine ligand is noted. Utility of the products is demonstrated by site- and chemoselective transformations that afford valuable alkenyl and allyl organoborons.
Organic Letters published new progress about Alkynylation. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,3-Dimethoxybenzene.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem