Feng, Qiang published the artcileDesign, synthesis, and applications of stereospecific 1,3-diene carbonyls, Recommanded Product: 4-Methoxyphenylacetic acid, the main research area is furan diazophenylacetate cyclopropanation diastereoselective rearrangement tandem reaction; phenylfuranylpropenal preparation; diazophenylacetate furan cyclopropanation diastereoselective rearrangement tandem reaction; oxophenylhexadienoate preparation; phenyl tolylsulfonylhydrazonohexadienoate arylboronic acid reductive coupling; aryl phenylhexadienoate preparation; indole phenyl tolylsulfonylhydrazonohexadienoate rhodium catalyst annulation; alkylcyclopentaindolyl phenylpropenoate preparation.
The strategy toward the synthesis of various 1,3-dienals or 1,3-dienones was disclosed between diazo compounds and furans, which features metal-free, additive-free, broad functional group tolerance and readily accessible starting materials. Notably, this strategy was applicable in both intramol. and intermol. protocols. Mechanistic studies suggested that the reactions undergo a cyclopropanation/rearrangement sequence. With an E/E-1,3-dienal, corresponding N-tosylhydrazones were readily prepared and subjected to phenylboronic acid to form a double bond migration product and indoles to construct a five-member ring via [3 + 2] annulation reaction.
Science China: Chemistry published new progress about [3+2] Cycloaddition reaction. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Recommanded Product: 4-Methoxyphenylacetic acid.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem