Xie, Qiqiang published the artcileAza-Matteson Reactions via Controlled Mono- and Double-Methylene Insertions into Nitrogen-Boron Bonds, Synthetic Route of 5961-59-1, the main research area is aminoborane preparation azaMatteson controlled methylene insertion reaction; aminobutanyldinitrobenzoate preparation crystal structure; mol structure amino butanyldinitrobenzoate; amine secondary borylation; amino alc preparation.
B-homologation reactions represent an efficient and programmable approach to prepare alkylboronates, which are valuable and versatile synthetic intermediates. The typical B-homologation reaction, also known as the Matteson reaction, involves formal carbenoid insertions into C-B bonds. Here the authors report the development of aza-Matteson reactions via carbenoid insertions into the N-B bonds of aminoboranes. By changing the leaving groups of the carbenoids and altering Lewis acid activators, selective mono- and double-methylene insertions can be realized to access various α- and β-B-substituted tertiary amines, resp., from common secondary amines. The derivatization of complex amine-containing bioactive mols., diverse functionalization of the boronate products, and sequential insertions of different carbenoids also were achieved.
Journal of the American Chemical Society published new progress about Boranes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (aminoboranes). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Synthetic Route of 5961-59-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem