The synthetic route of 1075-11-2 has been constantly updated, and we look forward to future research findings.
1075-11-2, 6-Fluoroisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
4-Chloro-6-fluoro-isoquinoline (24) EPO A solution of 1.5 g 6-fluoro-isoquinoline (23) in 4.5 ml sulfuryl chloride was heated to 60 0C in a microwave reactor (CEM Discovery) for 8 h. After cooling to room temperature the mixture was poured on ice and extracted three times with CHCI3. After drying over Na2SO4 the solvent was distilled off and the crude product was purified by flash chromatography to yield 930 mg of compound 24. LCMS Method No. 1 , retention time 1.37 min, detected mass 182.01 [M+H]+, 1075-11-2
The synthetic route of 1075-11-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SANOFI-AVENTIS DEUTSCHLAND GMBH; WO2007/240; (2007); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem