Ren, Jiangmeng published the artcileStudies towards DIAD promoted N-demethylation of N,N-dimethylanilines, Synthetic Route of 5961-59-1, the main research area is methylaniline preparation; dimethylaniline demethylation diisopropyl azodicarboxylate.
The demethylation of N,N-dimethylanilines promoted by diisopropyl azodicarboxylate (DIAD) to provide N-methylanilines was achieved in this paper. This protocol featured with mild reaction condition, simple operation and moderate to good yield. The intermediates were isolated and identified by means of spectroscopy methods. The reaction mechanism was investigated exptl. and further verified by theor. calculations This method could be applied to the study of the metabolites of medicines containing N,N-dimethylaniline fragments.
Tetrahedron Letters published new progress about Demethylation. 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Synthetic Route of 5961-59-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem