Nobile, Enzo published the artcileC-H Electrophilic (phenylsulfonyl)difluoromethylation of (hetero)arenes with a newly designed reagent, Computed Properties of 151-10-0, the main research area is aniline heteroarene electrophilic phenylsulfonyl difluoromethylation benzenesulfonyl difluoromethyldibenzothiophenium triflate.
The synthesis of an original electrophilic difluoromethylating reagent was successfully achieved upon a straightforward protocol (3 steps). Like a Swiss army knife, this bench-stable reagent allowed the functionalization of various classes of compounds under mild and transition metal-free conditions. Hence, an efficient and operationally simple tool for the construction of C(sp2)-, C(sp3)- and S-CF2SO2Ph bonds was provided, expanding the chem. space of PhSO2CF2-containing mols. Late-stage functionalization of bioactive mols. and the synthesis of PhSO2CF2- and HCF2-analogs of Lidocaine were also successfully achieved.
Chemical Communications (Cambridge, United Kingdom) published new progress about Difluoromethylation (phenylsulfonyl). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Computed Properties of 151-10-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem