Krieg, Reimar published the artcileFirst Synthesis of Highly Chemiluminescent Benzo[b]furan-2(3H)-ones Bearing a Urea Substructure, Synthetic Route of 598-50-5, the main research area is chemiluminescent dialkylaminocarbonylaminobenzofuranone preparation fluorescence.
A series of benzo[b]furan-2(3H)-ones (coumaran-2-ones) bearing a urea substructure, namely derivatives of 3-(aminocarbonylamino)benzo[b]furan-2(3H)-one, was prepared for the first time. The accessibility of these compounds through an electrophilic α-amidoalkylation approach of phenols (Tscherniac-Einhorn reaction) in the key step as well as the chemiluminescence (CL) properties of the desired compounds are strongly dependent on the substitution patterns at the urea moiety. Competing reaction pathways are discussed and an improved one pot synthetical approach of also general interest is presented. In conclusion, especially N,N-dialkylaminocarbonylamino-derivatives of benzo[b]furan-2(3H)-ones exhibit a strong flash like blue CL upon treatment with bases such as 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in the presence of oxygen or hydrogen peroxide. Comparative physico-chem. investigations revealed that novel compounds outperform their urethane-analogs in terms of CL-intensity and the speed of the decay making them potentially useful as new tools for CL-based applications on the short time scale.
Helvetica Chimica Acta published new progress about Chemiluminescence. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Synthetic Route of 598-50-5.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem