Wang, Ming-Ming published the artcileOxidative Fluorination of Cyclopropylamides through Organic Photoredox Catalysis, Category: isoquinoline, the main research area is oxidative ring opening fluorination cyclopropylamide cyclobutylamide organic photoredox catalysis; aminocyclopropanes; benzophenone; fluorination; photocatalysis; ring-opening.
We report an oxidative ring-opening strategy to transform cyclopropylamides and cyclobutylamides into fluorinated imines. The imines can be isolated in their more stable hemiaminal form, with the fluorine atom installed selectively at the γ or δ position. Both inexpensive benzophenone with UVA light or organic and inorganic dyes with blue light could be used as photoredox catalysts to promote this process. Various fluorinated amines were then obtained by nucleophilic attack on the hemiaminals in one pot, giving access to a broad range of useful building blocks for medicinal chem.
Angewandte Chemie, International Edition published new progress about Amines Role: SPN (Synthetic Preparation), PREP (Preparation) (fluoro amines). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Category: isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem