Maddila, Surya Narayana published the artcileAn eco-friendly approach for synthesis of novel substituted 4H-chromenes in aqueous ethanol under ultra-sonication with 94% atom economy, Quality Control of 86-51-1, the main research area is chromene preparation ultrasonication green chem; aryl aldehyde active methylene compound dimedone three component cyclization.
An operational approach for synthesis of eleven substituted 4H-chromene derivatives I (R = 2-CH3OC6H4, 4-CF3C6H4, pyridin-3-yl, etc.; R1 = Me, Et) by one-pot, three-component reaction of aromatic aldehydes RCHO, Me/Et cyanoacetate and 5,5 di-Me 1,3-cyclohexadione through ultrasound irradiation, in the presence of aqueous ethanol under catalyst-free condition is reported. Different spectral methods, including 1H, 13C and 15N NMR and HRMS were utilized to characterize the new mols. Benefits of the eco-friendly method are fast reaction (10 min), excellent yields (92-98%), no column chromatog. and no byproducts. Reaction offers 94% atom economy and 100% carbon capture.
Journal of Molecular Structure published new progress about Aryl aldehydes, heteroaryl Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Quality Control of 86-51-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem