Rokade, Balaji V. published the artcileSynthesis of α-Aryl-Oxindoles by Friedel-Crafts Alkylation of Arenes, Related Products of isoquinoline, the main research area is arylindole preparation; isatin diethylphosphite arene phospho Brook rearrangement Friedel Crafts reaction.
Synthesis of α-aryl-oxindoles was reported from isatin via a two-step procedure involving a phospha-Brook rearrangement and a Friedel-Crafts alkylation in a one-pot procedure. The use of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as solvent significantly extended the reaction substrate scope to include relatively less electron rich arenes including benzene. This new alkylation method is fast, straightforward and allows for the direct introduction of the oxindole moiety onto a range of aromatic compounds including phenols. Addnl., the application of arylated products was shown in decarboxylative asym. allylation and protonation.
Journal of Organic Chemistry published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Related Products of isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem