Biswal, Priyabrata published the artcilePalladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol, Application In Synthesis of 86-51-1, the main research area is methyl ketone preparation; diaryl propenol alc isomerization methylation palladium catalyst; aryl propenol alc isomerization methylation palladium catalyst.
One-pot synthesis of α-Me ketones RC(O)CH(R1)CH2R2 (R = Ph, 4-methoxyphenyl, naphthalen-2-yl, furan-2-yl, etc.; R1 = Me, Et, n-Bu; R2 = H, Ph, naphthalen-1-yl, thiophen-2-yl, etc.) starting from 1,3-diaryl propenols RCH(OH)CH=CHR2 or 1-aryl propenols RCH(OH)CH=CH2 and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by com. available Pd(OAc)2 with H2O as the only byproduct. Mechanistic studies and deuterium labeling experiments indicate the involvement of isomerization of allyl alc. followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.
Advanced Synthesis & Catalysis published new progress about Aliphatic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Application In Synthesis of 86-51-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem