Pham, Phuc H. published the artcileFunctionalization of C-H bonds in acetophenone oximes with arylacetic acids and elemental sulfur, Synthetic Route of 104-01-8, the main research area is fused thienothiazole preparation; acetophenone ketoxime arylacetic acid sulfur coupling.
Fused thieno[3,2-d]thiazoles were synthesized via a coupling of acetophenone ketoximes, arylacetic acids, and elemental sulfur in the presence of Li2CO3 base. Functionalities including chloro, bromo, fluoro, trifluoromethyl, and pyridyl groups were compatible with reaction conditions. High yields and excellent regioselectivities were obtained even if meta-substituted ketoxime acetates were used. Et esters of heteroarylacetic acids were competent substrates, which is very rare in the literature. This method would offer a convenient protocol to afford polyheterocyclic structures from simple substrates.
RSC Advances published new progress about Carboxylic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Synthetic Route of 104-01-8.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem