Mouries, Virginie published the artcileRadical β-elimination of a sulfinyl group to afford allenes, Safety of 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, the main research area is allene preparation; sulfoxide vinyl radical beta elimination.
An unprecedented radical β-elimination of vinyl sulfoxides, e.g. I (R = PhSO), obtained in two steps from the corresponding aldehydes or ketones and Ph vinyl sulfoxide, opened a new route to functionalized allenes, e.g. II. The radical translocation stratagem could also be used to trigger the β-elimination of the sulfinyl radical. Studies on the effect of the nature of the sulfur group on a common precursor showed that vinyl sulfimide I (R = PhSNTs) reacts similarly to vinyl sulfoxide I (R = PhSO), whereas vinyl sulfide I (R = PhS), vinyl sulfone I (R = PhSO2), and vinylsulfinyl imine I (R = PhSONTs) gave no allene II.
European Journal of Organic Chemistry published new progress about Allenes Role: SPN (Synthetic Preparation), PREP (Preparation). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Safety of 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem