891782-60-8,891782-60-8, 7-Bromo-3,4-dihydro-2H-isoquinolin-1-one is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
WXBB-2 (100.00 mg, 442.34 mumol, 1.00 eq), WX012-3 (110.00 mg, 900.38 mumol, 2.04 eq), cuprous iodide (43.00 mg, 225.78 mumol, 0.51 eq), 8-hydroxyquinoline (33.00 mg, 227.34 mumol, 39.29 muL, 0.51 eq), and potassium carbonate (92.00 mg, 665.65 mumol, 1.50 eq) were dissolved in dimethyl sulfoxide (15.00 mL), then purged with nitrogen three times, and the reaction was stirred at 130 C. for 16 hours. After the reaction was completed, the reaction solution was added with water (25 mL), and then extracted with dichloromethane (20 mL*3). The organic phases were combined, dried over anhydrous sodium sulfate (10 g), filtered and the filtrate was dried on a rotary evaporator. The obtained oil was separated and purified by Prep-TLC (ethyl acetate). Product WX012-4 was obtained, MSm/z: 268.1 [M+H]+.
891782-60-8 7-Bromo-3,4-dihydro-2H-isoquinolin-1-one 25067330, aisoquinoline compound, is more and more widely used in various fields.
Reference£º
Patent; FUJIAN COSUNTER PHARMACEUTICAL CO., LTD.; Wu, Chengde; Yu, Tao; Li, Ning; Chen, Shuhui; US2019/375728; (2019); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem