Ke, Lei’s team published research in Organic Letters in 2019-06-07 | CAS: 1205-17-0

Organic Letters published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Formula: C11H12O3.

Ke, Lei published the artcileCatalytic Selective Oxidative Coupling of Secondary N-Alkylanilines: An Approach to Azoxyarene, Formula: C11H12O3, the main research area is azoxyarene preparation anticancer catalyst oxidative coupling secondary alkylaniline.

Azoxyarenes are among important scaffolds in organic mols. Direct oxidative coupling of primary anilines provides a concise fashion to construct them. However, whether these scaffolds can be prepared from secondary N-alkylanilines is not well explored. Here, the authors present a catalytic selective oxidative coupling of secondary N-alkylaniline to afford azoxyarene with tungsten catalyst under mild conditions. In addition, azoxy can be viewed as a bioisostere of alkene and amide. Several “”azoxyarene analogs”” of the corresponding bioactive alkenes and amides showed comparable promising anticancer activities.

Organic Letters published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Formula: C11H12O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem