Leung, Gulice Yiu Chung published the artcileEfficient and Practical Synthesis of Sulfonamides Utilizing SO2 Gas Generated On Demand, HPLC of Formula: 151-10-0, the main research area is sulfonamide preparation continuous flow; amine organometallic compound demetalation.
A simple and practical protocol was developed for the synthesis of sulfonamides RSO2R1 (R = Ph, 4-fluorophenyl, 2-benzofuranyl, etc; R1 = NH2, NHMe, morpholin-4-yl, benzyl, cyclopropyl, etc.) by reacting organometallic reagents RM (M = MgBr, Li) with SO2 gas generated on demand. SO2 was generated from readily available reagents safely in a highly contained and controlled fashion. The protocol allows the synthesis of sulfonamides without using either atom-inefficient SO2 surrogates or a SO2 cylinder that requires stringent storage regulations in the laboratory The protocol was successfully applied to the synthesis of sildenafil.
Organic Process Research & Development published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, HPLC of Formula: 151-10-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem