Li, Xia published the artcileSolid-phase extraction coupled with ultra high performance liquid chromatography and electrospray tandem mass spectrometry for the highly sensitive determination of five iodinated X-ray contrast media in environmental water samples, Computed Properties of 117-96-4, the main research area is solid phase extraction ultraHigh performance liquid chromatog electrospray; HPLC mass spectrometry determination iodinated Xray contrast media water; Iodinated contrast media; Solid-phase extraction; Tandem mass spectrometry; Ultra high performance liquid chromatography; Water analysis.
A highly sensitive method based on solid-phase extraction and ultra high performance liquid chromatog. with electrospray tandem mass spectrometry has been developed for simultaneous determination of 5 iodinated x-ray contrast media in environmental water samples. Various solid-phase extraction cartridges have been evaluated and a combination of LiChrolute EN and ENVI-Carb solid phase extraction cartridges was selected for sample enrichment. The method was comprehensively validated on groundwater, tap water, surface water, drinking water, and wastewater by the conventional procedures: linearity, method detection limits, accuracy and precision, matrix effects. Good linearity (R2 >0.999), low detection limits (0.4-8.1 ng/L), satisfactory recoveries (55.1-109.5%) and precision (0.8-10.0% for intra-day precisions and 0.6-16.5% for inter-day precisions) were obtained for all the target compounds Iopamidol, iohexol, and diatrizoate in some matrixes were affected by matrix effects, which were slightly eased by using the isotope-labeled internal standard The method was applied to the anal. of water from Shanghai, China, with detected concentrations up to 2200±200 and 9000±1000 ng/L for iohexol and iopamidol, resp.
Journal of Separation Science published new progress about Liquid chromatography-mass spectrometry. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Computed Properties of 117-96-4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem