Brandolese, Arianna published the artcileEnantioselective N-Acylation of Biginelli Dihydropyrimidines by Oxidative NHC Catalysis, Formula: C2H6N2O, the main research area is acylated dihydropyrmiidine enantioselective synthesis acylation heterocyclic carbene catalysis; enantioselective acylation Biginelli dihydropyrimidine enal heterocyclic carbene catalysis.
The oxidative N-acylation reaction of 3,4-dihydropyrimidin-2-(1H)-ones (DHPMs) with enals and N-heterocyclic carbene (NHC) catalysts is described. The reaction proceeds in the presence of quinone oxidant without addnl. acyl transfer agents and in the asym. variant produces pharmaceutically relevant N3-acylated products with good-to-moderate enantioselectivity.
European Journal of Organic Chemistry published new progress about Acylation catalysts (enantioselective). 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Formula: C2H6N2O.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem