Triandafillidi, Ierasia’s team published research in Organic Letters in 2019-07-19 | CAS: 1205-17-0

Organic Letters published new progress about Corey-Chaykovsky reaction (Johnson-). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Formula: C11H12O3.

Triandafillidi, Ierasia published the artcileSynthesis of γ-Lactones Utilizing Ketoacids and Trimethylsulfoxonium Iodide, Formula: C11H12O3, the main research area is gamma hydroxymethyl lactone preparation; Johnson Corey Chaykovsky reaction gamma ketoacid methylsulfoxonium iodide; delta lactone gamma ketoamide cyclocondensation methylsulfoxonium iodide.

γ-Ketoacids, a δ-ketoacid, and a γ-ketoamide underwent Johnson-Corey-Chaykovsky epoxidation with trimethylsulfoxonium iodide and NaH in DMSO to yield γ-(hydroxymethyl)-γ-lactones, a δ-(hydroxymethyl)-δ-lactone, and a γ-(hydroxymethyl)-γ-lactam in 22-76% yields. The method was used in an attempted synthesis of (+)-asperolide C; (-)-epi-asperolide C was obtained in two steps from (+)-podocarpic acid.

Organic Letters published new progress about Corey-Chaykovsky reaction (Johnson-). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Formula: C11H12O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem